Additional file 1: of Temple syndrome in a patient with variably methylated CpGs at the primary MEG3/DLK1:IG-DMR and severely hypomethylated CpGs at the secondary MEG3:TSS-DMR

Table S1. Primers utilized in this study. Table S2. Methylation levels (β-values) of each CpG site in leukocyte DNA samples. Table S3. The results of micosatellite analysis. Figure S1. Methylation analyses of the H19/IGF2:IG-DMR, MEG3:TSS-DMR, and GNAS A/B:TSS-DMR, using leukocyte gDNA samples. Figure S2. Lack of UPD (14) mat and microdeletion in this patient. Figure S3. Representative data in patients with both hypomethylation-type and hypermethylation-type of MLID in the absence of a mutation in causative or candidate genes for MLID. (PDF 1007 kb)