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TYROBP genetic variants in early-onset Alzheimer's disease
- Source :
- Neurobiology of aging
- Publication Year :
- 2016
-
Abstract
- We aimed to identify new candidate genes potentially involved in early-onset Alzheimer's disease (EOAD). Exome sequencing was conducted on 45 EOAD patients with either a family history of Alzheimer's disease (AD
- Subjects :
- 0301 basic medicine
Adult
Male
Aging
Candidate gene
Down-Regulation
Gene Expression
Disease
Biology
Bioinformatics
Article
Cohort Studies
03 medical and health sciences
0302 clinical medicine
Alzheimer Disease
Genetic variation
medicine
Humans
Early-onset Alzheimer's disease
Exome
Receptors, Immunologic
Exome sequencing
Genetic Association Studies
Adaptor Proteins, Signal Transducing
Aged
Genetics
Aged, 80 and over
Membrane Glycoproteins
TREM2
General Neuroscience
Genetic Variation
Membrane Proteins
Middle Aged
medicine.disease
030104 developmental biology
Mutation
Female
Neurology (clinical)
Human medicine
Geriatrics and Gerontology
Alzheimer's disease
Sequence Analysis
030217 neurology & neurosurgery
Developmental Biology
HeLa Cells
Subjects
Details
- Language :
- English
- ISSN :
- 01974580
- Database :
- OpenAIRE
- Journal :
- Neurobiology of aging
- Accession number :
- edsair.doi.dedup.....1bc30c35e2cef7d093c29f5f42ca5e6c