Back to Search
Start Over
Sesquiterpenoids from Artemisia argyi and their NO production inhibitory activity in RAW264.7 cells
Sesquiterpenoids from Artemisia argyi and their NO production inhibitory activity in RAW264.7 cells
- Publication Year :
- 2019
- Publisher :
- Taylor & Francis, 2019.
-
Abstract
- Investigation into the chemical diversity of Artemisia argyi led to the discovery of two new (1, 4) and four known (2-3, 5-6) sesquiterpenoids. The new structures were determined via extensive spectroscopic data, including IR, UV, MS, and NMR, and the absolute configurations of these compounds were elucidated by calculated ECD method. All isolates were tested for their inhibitory activity against NO production in RAW 264.7 macrophages, and the isolated sesquiterpenoids exhibited NO production inhibitory activity with IC50 values ranging from 1.91 to 36.52 μM.
- Subjects :
- Artemisia argyi
010405 organic chemistry
Chemistry
Stereochemistry
Organic Chemistry
Plant Science
Inhibitory postsynaptic potential
01 natural sciences
Biochemistry
0104 chemical sciences
Analytical Chemistry
010404 medicinal & biomolecular chemistry
Chemical diversity
Ic50 values
No production
Subjects
Details
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....1d0f37d9f11d09f3933eaa8b38a53aa7
- Full Text :
- https://doi.org/10.6084/m9.figshare.10120799.v1