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Recent advances in proteomic studies of adipose tissues and adipocytes
- Source :
- International Journal of Molecular Sciences, International Journal of Molecular Sciences, Vol 16, Iss 3, Pp 4581-4599 (2015)
- Publication Year :
- 2014
-
Abstract
- Obesity is a chronic disease that is associated with significantly increased levels of risk of a number of metabolic disorders. Despite these enhanced health risks, the worldwide prevalence of obesity has increased dramatically over the past few decades. Obesity is caused by the accumulation of an abnormal amount of body fat in adipose tissue, which is composed mostly of adipocytes. Thus, a deeper understanding of the regulation mechanism of adipose tissue and/or adipocytes can provide a clue for overcoming obesity-related metabolic diseases. In this review, we describe recent advances in the study of adipose tissue and/or adipocytes, focusing on proteomic approaches. In addition, we suggest future research directions for proteomic studies which may lead to novel treatments of obesity and obesity-related diseases.
- Subjects :
- Proteomics
medicine.medical_specialty
Proteomics methods
Proteome
adipocytes
Adipose tissue
Review
Biology
Catalysis
adipogenesis
Inorganic Chemistry
lcsh:Chemistry
Internal medicine
medicine
Animals
Humans
Protein Isoforms
Obesity
Physical and Theoretical Chemistry
Molecular Biology
lcsh:QH301-705.5
Spectroscopy
browning
Mechanism (biology)
Organic Chemistry
Lipid metabolism
General Medicine
medicine.disease
Lipid Metabolism
Computer Science Applications
adipose tissue
Endocrinology
Chronic disease
lcsh:Biology (General)
lcsh:QD1-999
Adipogenesis
Subjects
Details
- ISSN :
- 14220067
- Volume :
- 16
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- International journal of molecular sciences
- Accession number :
- edsair.doi.dedup.....1d28a3d1f973b3365f07d48222ba7889