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Toxicity and Mutagenicity of the Molluscicidal Plant Ambrosia Maritima L

Authors :
F. Alard
C. Stievenart
Ph. Vanparys
Stanny Geerts
L. Thilemans
Source :
Drug and Chemical Toxicology. 14:353-373
Publication Year :
1991
Publisher :
Informa UK Limited, 1991.

Abstract

The acute and subchronic toxicity of the mol-luscicidal plant. Ambrosia maritima L., has been tested on rats. No toxic signs could be detected neither after oral administration of 5 g/kg of dried leaves of the plant as a powder or as a methanolic extract, nor after the incorporation of 50, 000 ppm powdered leaves in the feed during 4 weeks.Using an aqueous extract of the plant material of A. maritima or using ambrosin, one of the active molluscicidal components of the plant, no mutagenic activity could be detected in the S. typhimurium strains TA97, TA 98, TA1538, TA100 and TA1535.

Details

ISSN :
15256014 and 01480545
Volume :
14
Database :
OpenAIRE
Journal :
Drug and Chemical Toxicology
Accession number :
edsair.doi.dedup.....1d436bcc006fdd747090d098e4e3c25f
Full Text :
https://doi.org/10.3109/01480549109011639