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Loss‐of‐function mutation of the calcium sensor <scp>CBL</scp> 1 increases aluminum sensitivity in Arabidopsis
- Source :
- New Phytologist. 214:830-841
- Publication Year :
- 2017
- Publisher :
- Wiley, 2017.
-
Abstract
- Despite the physiological importance of aluminum (Al) phytotoxicity for plants, it remained unknown if, and how, calcineurin B-like calcium sensors (CBLs) and CBL-interacting protein kinases (CIPKs) are involved in Al resistance. We performed a comparative physiological and whole transcriptome investigation of an Arabidopsis CBL1 mutant (cbl1) and the wild-type (WT). cbl1 plants exudated less Al-chelating malate, accumulated more Al, and displayed a severe root growth reduction in response to Al. Genes involved in metabolism, transport, cell wall modification, transcription and oxidative stress were differentially regulated between the two lines, under both control and Al stress treatments. Exposure to Al resulted in up-regulation of a large set of genes only in WT and not cbl1 shoots, while a different set of genes were down-regulated in cbl1 but not in WT roots. These differences allowed us, for the first time, to define a calcium-regulated/dependent transcriptomic network for Al stress responses. Our analyses reveal not only the fundamental role of CBL1 in the adjustment of central transcriptomic networks involved in maintaining adequate physiological homeostasis processes, but also that a high shoot-root dynamics is required for the proper deployment of Al resistance responses in the root.
- Subjects :
- 0106 biological sciences
0301 basic medicine
Physiology
Mutant
Arabidopsis
Malates
Down-Regulation
chemistry.chemical_element
Plant Science
Calcium
Biology
Genes, Plant
Plant Roots
01 natural sciences
Transcriptome
03 medical and health sciences
Gene Expression Regulation, Plant
Loss of Function Mutation
Stress, Physiological
Calcium-binding protein
Botany
Gene
Cell wall modification
Arabidopsis Proteins
Kinase
Calcium-Binding Proteins
biology.organism_classification
Cell biology
Gene Ontology
030104 developmental biology
chemistry
Aluminum
010606 plant biology & botany
Subjects
Details
- ISSN :
- 14698137 and 0028646X
- Volume :
- 214
- Database :
- OpenAIRE
- Journal :
- New Phytologist
- Accession number :
- edsair.doi.dedup.....1d8dd2fe095b658940f5be3742ad6baa