The comparative effects of intensive glucose lowering in diabetes patients aged below or above 65 years: Results from the <scp>ADVANCE</scp> trial

AIMS: For relatively old patients with diabetes, current guidelines recommend adjustment of glycaemic goals based on patients&#39; cognitive function, or coexisting chronic illnesses. However, the evidence which supports the efficacy and safety of intensive glucose lowering in older patients with diabetes is scarce. The objective of the present study was to compare the efficacy and safety of intensive glucose lowering in patients with type 2 diabetes stratified by age (