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Etiology and clinical profile of childhood optic nerve atrophy at a tertiary eye care center in South India
- Source :
- Indian Journal of Ophthalmology, Indian Journal of Ophthalmology, Vol 63, Iss 4, Pp 359-360 (2015)
- Publication Year :
- 2015
- Publisher :
- Medknow Publications & Media Pvt Ltd, 2015.
-
Abstract
- Sir, I have two comments on the interesting study by Chinta et al.[1] First, Chinta et al.[1] addressed that hypoxic ischemic encephalopathy (HIE) seen in 41% of patients was the most frequent cause of childhood optic nerve atrophy (ONA), followed by idiopathic (30%), hydrocephalus (7%), compressive etiology (5%), infective (6%), congenital (2%), inflammatory (2%), respectively. I presume that the actual prevalence of HIE in the studied cohort is higher than 41% already reported. This is based on the following two points. (1) It is obvious that HIE is a common and serious complication of prematurity. The increasing rates of preterm births coupled with better survival of these infants have resulted in the higher prevalence of systemic and ocular complications associated with prematurity. In addition to retinopathy of prematurity, infants who are born preterm may suffer from severe visual impairment as a result of HIE, hypoglycemia, and other metabolic imbalances. The effect of these processes on the anterior visual pathway may result in optic atrophy, optic nerve hypoplasia or optic disc cupping and affection of the posterior visual pathway leads to cortical visual impairment. Other ocular associations include strabismus, nystagmus, and ocular motor abnormalities such as tonic down gaze and defective saccades and pursuits.[2] In the last decade, improved survival of infants with low birth weight (LBW) has been achieved in many developed countries. However, Indian subcontinent has still the highest child mortality rates along with a very high frequency of prematurity and LBW. Maternal education, exposure to passive smoking, age at first pregnancy ≥25 years, birth interval
- Subjects :
- Pediatrics
medicine.medical_specialty
Birth weight
Population
India
Cortical visual impairment
Tertiary Care Centers
lcsh:Ophthalmology
medicine
Humans
education
Letters to the Editor
Pregnancy
Optic nerve hypoplasia
education.field_of_study
business.industry
Retinopathy of prematurity
Optic Nerve
medicine.disease
Ophthalmology
Low birth weight
Optic Atrophy
lcsh:RE1-994
Etiology
medicine.symptom
Atrophy
business
Subjects
Details
- Language :
- English
- ISSN :
- 19983689 and 03014738
- Volume :
- 63
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Indian Journal of Ophthalmology
- Accession number :
- edsair.doi.dedup.....1e802721474692ff35b5f00e2af29dae