Back to Search Start Over

Plasma Levels after Repository Injections of Penicillin in Water-in-Oil Emulsions

Authors :
H. W. Harris
Clare Wilcox
Maxwell Finland
Source :
Experimental Biology and Medicine. 63:199-201
Publication Year :
1946
Publisher :
SAGE Publications, 1946.

Abstract

ConclusionsThe previous observation that only a slight and inconstant prolongation of penicillin blood levels is obtained by the use of a water-in-oil emulsion is confirmed. The present findings suggest further that a substantial increase in the intramuscular dose of penicillin in the same volume of saline will give considerably higher and better sustained plasma levels than the smaller dose given in a water-in-oil emulsion and the disadvantages of the latter method are thus avoided.

Details

ISSN :
15353699 and 15353702
Volume :
63
Database :
OpenAIRE
Journal :
Experimental Biology and Medicine
Accession number :
edsair.doi.dedup.....1e9e9069cbe35866f91320b97017d4d2
Full Text :
https://doi.org/10.3181/00379727-63-15546