Morphological changes in eosinophils are reliable markers of the severity of an acute asthma exacerbation in children

MI Muniz-Junqueira, SM Barbosa-Marques, LF Junqueira Jr. Allergy. 2013;68(7):911–920 The goal of this study was to determine if morphologic changes in blood eosinophils can be used for early identification of the severity of an acute asthma exacerbation in children. Children were selected sequentially in an emergency care unit or asthma outpatient clinic. They comprised a group of 15 healthy children (5 girls and 10 boys; ages 4–14 years) without asthma or a personal of familial history of allergy, a group of 15 asthmatic children with variable disease severity (3 girls and 12 boys; ages 2–12 years) seen at a symptom-free …