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The role of NBI with flexible video-endoscope in the follow-up of head and neck cancer patients: a prospective study
- Publication Year :
- 2022
-
Abstract
- Purpose: Narrow band imaging (NBI) enhances mucosal vasculature and could help in the identification of recurrences. We assessed the effectiveness of NBI with flexible video-endoscope in the early detection of recurrence after treatment of head and neck squamous cell carcinoma, its diagnostic advantage over high-definition white-light (HD WL) endoscopy, also in relation to recurrence site, and the influence of previous radiotherapy (RT) or chemotherapy (CT). Moreover, we investigated the association between index tumor site and the risk of developing recurrence, and the relation between index tumor site and recurrence site. Methods: From January 2018 to November 2020, 160 patients previously treated with surgery and/or RT ± CT were evaluated using NBI with flexible video-endoscope. Sensitivity, specificity, positive/negative predictive value, and accuracy were calculated for NBI and HD WL, and compared using the McNemar test. The Fisher exact test was used to compare the other associations investigated. Results: The difference between NBI and HD WL sensitivity was statistically significant (p < 0.001). The NBI diagnostic advantage was 62.5%, highest in the hypopharynx (p = 0.05), and was not influenced by previous RT or CT (p = 0.49). Index tumor site statistically related with recurrence site (p < 0.001), but not with the risk of developing recurrence (p = 0.81). Conclusion: NBI with flexible video-endoscope could represent a valid option to detect recurrence early during the follow-up, especially in a difficult-to-visualize site such as the hypopharynx.
- Subjects :
- medicine.medical_specialty
medicine.medical_treatment
Sensitivity and Specificity
Narrow Band Imaging
symbols.namesake
McNemar's test
Recurrence
medicine
Humans
Prospective Studies
Prospective cohort study
Early Detection of Cancer
Fisher's exact test
Endoscopes
medicine.diagnostic_test
Radiotherapy
business.industry
Follow-up
Head and neck cancer
Early detection
NBI-flexible-video-endoscopy
Second primary tumor
General Medicine
medicine.disease
Head and neck squamous-cell carcinoma
Endoscopy
Radiation therapy
Otorhinolaryngology
Head and Neck Neoplasms
symbols
Radiology
business
Follow-Up Studies
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....1fe24e6c58fdc70aef652dd124e5cad6