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Erratum. Renal Effects of DPP-4 Inhibitor Sitagliptin or GLP-1 Receptor Agonist Liraglutide in Overweight Patients With Type 2 Diabetes: A 12-Week, Randomized, Double-Blind, Placebo-Controlled Trial. Diabetes Care 2016;39:2042-2050
- Source :
- Diabetes Care, 42(3). American Diabetes Association Inc., Tonneijck, L, Smits, M M, Muskiet, M H A, Hoekstra, T, Kramer, M H H, Danser, A H J, Ter Wee, P M, Diamant, M, Joles, J A & van Raalte, D H 2019, ' Erratum. Renal Effects of DPP-4 Inhibitor Sitagliptin or GLP-1 Receptor Agonist Liraglutide in Overweight Patients With Type 2 Diabetes : A 12-Week, Randomized, Double-Blind, Placebo-Controlled Trial. Diabetes Care 2016;39:2042-2050 ', Diabetes Care, vol. 42, no. 3 . https://doi.org/10.2337/dc19-er03, Tonneijck, L, Smits, M M, Muskiet, M H A, Hoekstra, T, Kramer, M H H, Danser, A H J, Ter Wee, P M, Diamant, M, Joles, J A & van Raalte, D H 2019, ' Erratum. Renal effects of DPP-4 inhibitor sitagliptin or GLP-1 receptor agonist liraglutide in overweight patients with type 2 diabetes : a 12-week, randomized, double-blind, placebo-controlled trial. Diabetes Care 2016;39:2042-2050 ', Diabetes Care, vol. 42, no. 3 . https://doi.org/10.2337/dc19-er03, Diabetes Care
- Publication Year :
- 2019
-
Abstract
- To investigate effects of dipeptidyl peptidase-4 inhibitor (DPP-4I) sitagliptin or glucagon-like peptide 1 (GLP-1) receptor agonist liraglutide treatment on renal hemodynamics, tubular functions, and markers of renal damage in overweight patients with type 2 diabetes without chronic kidney disease (CKD).In this 12-week, randomized, double-blind trial, 55 insulin-naïve patients with type 2 diabetes (mean ± SEM: age 63 ± 7 years, BMI 31.8 ± 4.1 kg/mAt week 12, GFR was not affected by sitagliptin (-6 mL/min/1.73 mTwelve-week treatment with sitagliptin or liraglutide does not affect measured renal hemodynamics. No sustained changes in tubular functions or alteration in renal damage markers were observed. The validity and clinical relevance of the slight sitagliptin-induced P
- Subjects :
- Male
medicine.medical_specialty
Endocrinology, Diabetes and Metabolism
Placebo-controlled study
030209 endocrinology & metabolism
Type 2 diabetes
Overweight
Kidney
Gastroenterology
Glucagon-Like Peptide-1 Receptor
Body Mass Index
03 medical and health sciences
0302 clinical medicine
Double-Blind Method
SDG 3 - Good Health and Well-being
Internal medicine
Diabetes mellitus
Renin
Internal Medicine
medicine
Humans
Hypoglycemic Agents
Insulin
030212 general & internal medicine
Dipeptidyl peptidase-4
Glucagon-like peptide 1 receptor
Aged
Glycated Hemoglobin
Advanced and Specialized Nursing
Dipeptidyl-Peptidase IV Inhibitors
Errata
business.industry
Liraglutide
Sitagliptin Phosphate
Sodium
Middle Aged
medicine.disease
Treatment Outcome
Diabetes Mellitus, Type 2
Sitagliptin
Potassium
Female
medicine.symptom
business
medicine.drug
Subjects
Details
- ISSN :
- 19355548 and 01495992
- Volume :
- 42
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Diabetes care
- Accession number :
- edsair.doi.dedup.....2070cabe84611a7f22ee79fafc2dce4c