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Erratum. Renal Effects of DPP-4 Inhibitor Sitagliptin or GLP-1 Receptor Agonist Liraglutide in Overweight Patients With Type 2 Diabetes: A 12-Week, Randomized, Double-Blind, Placebo-Controlled Trial. Diabetes Care 2016;39:2042-2050

Authors :
Daniël H. van Raalte
Trynke Hoekstra
Mark M. Smits
Michaela Diamant
Piet M. ter Wee
Jaap A. Joles
Marcel H.A. Muskiet
Lennart Tonneijck
A.H. Jan Danser
Mark H.H. Kramer
Internal medicine
Epidemiology and Data Science
Amsterdam Gastroenterology Endocrinology Metabolism
ACS - Diabetes & metabolism
Source :
Diabetes Care, 42(3). American Diabetes Association Inc., Tonneijck, L, Smits, M M, Muskiet, M H A, Hoekstra, T, Kramer, M H H, Danser, A H J, Ter Wee, P M, Diamant, M, Joles, J A & van Raalte, D H 2019, ' Erratum. Renal Effects of DPP-4 Inhibitor Sitagliptin or GLP-1 Receptor Agonist Liraglutide in Overweight Patients With Type 2 Diabetes : A 12-Week, Randomized, Double-Blind, Placebo-Controlled Trial. Diabetes Care 2016;39:2042-2050 ', Diabetes Care, vol. 42, no. 3 . https://doi.org/10.2337/dc19-er03, Tonneijck, L, Smits, M M, Muskiet, M H A, Hoekstra, T, Kramer, M H H, Danser, A H J, Ter Wee, P M, Diamant, M, Joles, J A & van Raalte, D H 2019, ' Erratum. Renal effects of DPP-4 inhibitor sitagliptin or GLP-1 receptor agonist liraglutide in overweight patients with type 2 diabetes : a 12-week, randomized, double-blind, placebo-controlled trial. Diabetes Care 2016;39:2042-2050 ', Diabetes Care, vol. 42, no. 3 . https://doi.org/10.2337/dc19-er03, Diabetes Care
Publication Year :
2019

Abstract

To investigate effects of dipeptidyl peptidase-4 inhibitor (DPP-4I) sitagliptin or glucagon-like peptide 1 (GLP-1) receptor agonist liraglutide treatment on renal hemodynamics, tubular functions, and markers of renal damage in overweight patients with type 2 diabetes without chronic kidney disease (CKD).In this 12-week, randomized, double-blind trial, 55 insulin-naïve patients with type 2 diabetes (mean ± SEM: age 63 ± 7 years, BMI 31.8 ± 4.1 kg/mAt week 12, GFR was not affected by sitagliptin (-6 mL/min/1.73 mTwelve-week treatment with sitagliptin or liraglutide does not affect measured renal hemodynamics. No sustained changes in tubular functions or alteration in renal damage markers were observed. The validity and clinical relevance of the slight sitagliptin-induced P

Details

ISSN :
19355548 and 01495992
Volume :
42
Issue :
3
Database :
OpenAIRE
Journal :
Diabetes care
Accession number :
edsair.doi.dedup.....2070cabe84611a7f22ee79fafc2dce4c