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The course of cognitive performance during inpatient treatment in patients with alcohol use disorder with no, mild or major neurocognitive disorders
- Source :
- Alcohol and Alcoholism, 56, 89-100, Alcohol and Alcoholism (Oxford, Oxfordshire), Alcohol and Alcoholism, 56, 1, pp. 89-100
- Publication Year :
- 2021
-
Abstract
- Aims In patients with a history of chronic alcohol abuse, neurocognitive disorders (NCD) are not uncommon. The current study aimed to explore the course of cognitive performance, as measured by the Montreal Cognitive Assessment (MoCA), and everyday cognitive functioning, as measured by the Patient Competency Rating Scale (PCRS), in a large group of patients with alcohol use disorder (AUD) admitted to the Center of Excellence for Korsakov and Alcohol-related Cognitive Impairments. Methods A multiple time-series design was used, in which the MoCA was administered at three time points of assessment, and the PCRS was completed by both the patient and a clinician at two time points, all during clinical treatment. Results A total of 524 patients were included, 71 of whom were diagnosed with AUD only, 284 with AUD and mild NCD (ARCI) and 169 with AUD, major NCD and fulfilling criteria for Korsakoff’s syndrome (KS). Conclusions Cognitive performance improved for all three groups during treatment, sustained abstinence and recovery from AUD. A low memory performance on the MoCA without improvement over time was predictive for KS, while improvement on this domain did not differentiate between AUD and ARCI. Changes in overall cognitive performance and orientation in patients with KS were positively related to changes in everyday cognitive functioning.<br />Short Summary Cognitive performance improves during treatment, sustained abstinence and recovery from AUD. Low memory performance without improvement over time predicted KS, while improvement in memory did not differentiate between AUD and ARCI. Changes in overall cognitive performance and orientation in KS patients were positively related to changes in everyday cognitive functioning.
- Subjects :
- Adult
Male
050103 clinical psychology
medicine.medical_specialty
Alzheimer`s disease Donders Center for Medical Neuroscience [Radboudumc 1]
media_common.quotation_subject
Neurocognitive Disorders
Alcohol use disorder
Article
Experimental Psychopathology and Treatment
Executive Function
03 medical and health sciences
All institutes and research themes of the Radboud University Medical Center
0302 clinical medicine
Alcohol-Induced Disorders, Nervous System
Memory
Rating scale
mental disorders
Humans
Medicine
Cognitive Dysfunction
AcademicSubjects/MED00860
0501 psychology and cognitive sciences
Cognitive skill
Effects of sleep deprivation on cognitive performance
Psychiatry
Aged
media_common
Aged, 80 and over
Neuro- en revalidatiepsychologie
business.industry
Neuropsychology and rehabilitation psychology
05 social sciences
Montreal Cognitive Assessment
Cognition
General Medicine
Middle Aged
Abstinence
Mental Status and Dementia Tests
medicine.disease
Hospitalization
Alcoholism
Alcoholic Korsakoff Syndrome
Female
business
Neurocognitive
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 07350414
- Volume :
- 56
- Database :
- OpenAIRE
- Journal :
- Alcohol and Alcoholism
- Accession number :
- edsair.doi.dedup.....2195b171892bd49d8cfb188fc2031e06