Palladium-Catalyzed Anti-Markovnikov Hydroalkylation of Homoallylic Alcohols Bearing β-Fluorines

Authors :: Xiaowei Lin
Feng-Ling Qing
Source :: Organic Letters. 15:4478-4481
Publication Year :: 2013
Publisher :: American Chemical Society (ACS), 2013.
Abstract: A palladium-catalyzed anti-Markovnikov hydroalkylation of β,β-difluorinated homoallylic alcohols with alkylzinc reagents has been developed. This method affords a wide range of synthetically useful gem-difluorinated compounds with good functional group compatibility.

Subjects :: Chemistry
Reagent
Organic Chemistry
Markovnikov's rule
chemistry.chemical_element
Organic chemistry
Physical and Theoretical Chemistry
Biochemistry
Catalysis
Palladium

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