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Optimization of psoriasis assessment system based on patch images
- Source :
- Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021), Scientific Reports
- Publication Year :
- 2021
- Publisher :
- Nature Portfolio, 2021.
-
Abstract
- Psoriasis is a chronic inflammatory skin disease that occurs in various forms throughout the body and is associated with certain conditions such as heart disease, diabetes, and depression. The psoriasis area severity index (PASI) score, a tool used to evaluate the severity of psoriasis, is currently used in clinical trials and clinical research. The determination of severity is based on the subjective judgment of the clinician. Thus, the disease evaluation deviations are induced. Therefore, we propose optimal algorithms that can effectively segment the lesion area and classify the severity. In addition, a new dataset on psoriasis was built, including patch images of erythema and scaling. We performed psoriasis lesion segmentation and classified the disease severity. In addition, we evaluated the best-performing segmentation method and classifier and analyzed features that are highly related to the severity of psoriasis. In conclusion, we presented the optimal techniques for evaluating the severity of psoriasis. Our newly constructed dataset improved the generalization performance of psoriasis diagnosis and evaluation. It proposed an optimal system for specific evaluation indicators of the disease and a quantitative PASI scoring method. The proposed system can help to evaluate the severity of localized psoriasis more accurately.
- Subjects :
- medicine.medical_specialty
Heart disease
Science
Clinical Decision-Making
Disease
macromolecular substances
Severity of Illness Index
Article
Medical research
Disease severity
Psoriasis
Image Interpretation, Computer-Assisted
Image Processing, Computer-Assisted
medicine
Humans
Segmentation
Skin
Multidisciplinary
Lesion segmentation
business.industry
Inflammatory skin disease
Health care
Disease Management
medicine.disease
Dermatology
Clinical trial
Erythema
Area Under Curve
Medicine
business
Subjects
Details
- Language :
- English
- ISSN :
- 20452322
- Volume :
- 11
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Scientific Reports
- Accession number :
- edsair.doi.dedup.....2237884aa6852c3692c59ad266e0cc9a