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SensApp: A FET-Open project for developing a supersensor able to detect Alzheimer's disease biomarkers in blood

Authors :
Reinhard Schwoediauer
Pier Luca Maffettone
Markku Känsäkoski
Volodymyr Tkachenko
Gaetano D'Avino
Emanuela Mazzon
Heidi Ottevaere
Martina Mugnano
Veronica Vespini
Danila del Giudice
Romina Rega
Simonetta Grilli
Yunfeng Nie
Simona Itri
Pietro Ferraro
Sara Coppola
Martin Kaltenbrunner
Sanna Uusitalo
Ferraro, Pietro
Rega, R.
Mugnano, M.
Del Giudice, D.
Itri, S.
Tkachenko, V.
Vespini, V.
Coppola, S.
Ferraro, P.
Ottevaere, H.
Nie, Y.
Uusitalo, S.
Schwoediauer, R.
Kaltenbrunner, M.
Kansakoski, M.
Mazzon, E.
Maffettone, P. L.
D'Avino, G.
Grilli, S.
Grilli, Simonetta
Ritsch-Marte, Monika
Hitzenberger, Christoph K.
Applied Physics and Photonics
Source :
Optical Methods for Inspection, Characterization, and Imaging of Biomaterials V, Rega, R, Mugnano, M, Del Giudice, D, Itri, S, Tkachenko, V, Vespini, V, Coppola, S, Ferraro, P, Ottevaere, H, Nie, Y, Uusitalo, S, Schwoediauer, R, Kaltenbrunner, M, Känsäkoski, M, Mazzon, E, Maffettone, P L, D'Avino, G & Grilli, S 2021, SensApp : A FET-Open project for developing a supersensor able to detect Alzheimer's disease biomarkers in blood . in P Ferraro, S Grilli, M Ritsch-Marte & C K Hitzenberger (eds), Optical Methods for Inspection, Characterization, and Imaging of Biomaterials V ., 1178605, International Society for Optics and Photonics SPIE, Proceedings of SPIE-The International Society for Optical Engineering, vol. 11786, Optical Methods for Inspection, Characterization, and Imaging of Biomaterials V 2021, Virtual, Online, Germany, 21/06/21 . https://doi.org/10.1117/12.2596966
Publication Year :
2021

Abstract

The goal of the SensApp FET-Open project is to develop an innovative super-sensor that will be able to detect Alzheimer’s disease (AD) biomarkers (β-amyloid, Tau and pTAU) in peripheral blood. Considering that nowadays an accurate diagnosis of AD requires the highly invasive withdrawal and analysis of cerebrospinal fluid, SensApp will represent a breakthrough in the field of AD diagnosis thanks to the ability to detect the early stage of the disease by a simple blood collection. We call Droplet-Split-and-Stack (DSS) the new technology that will emerge from SensApp. The achievement of SensApp goal is enabled by the interdisciplinary cooperation between different research institutions and one company involved in the key fields of the project, Vrije Universiteit Brussels, VTT Technical Research Centre of Finland, University of Linz, Ginolis Ltd, IRCCS Centre “Bonino Pulejo”, under the coordination of CNR-Institute of Applied Sciences and Intelligent Systems. This communication will illustrate the progress of the activities.

Details

ISBN :
978-1-5106-4406-9
978-1-5106-4407-6
ISBNs :
9781510644069 and 9781510644076
Database :
OpenAIRE
Journal :
Optical Methods for Inspection, Characterization, and Imaging of Biomaterials V, Rega, R, Mugnano, M, Del Giudice, D, Itri, S, Tkachenko, V, Vespini, V, Coppola, S, Ferraro, P, Ottevaere, H, Nie, Y, Uusitalo, S, Schwoediauer, R, Kaltenbrunner, M, Känsäkoski, M, Mazzon, E, Maffettone, P L, D'Avino, G & Grilli, S 2021, SensApp : A FET-Open project for developing a supersensor able to detect Alzheimer's disease biomarkers in blood . in P Ferraro, S Grilli, M Ritsch-Marte & C K Hitzenberger (eds), Optical Methods for Inspection, Characterization, and Imaging of Biomaterials V ., 1178605, International Society for Optics and Photonics SPIE, Proceedings of SPIE-The International Society for Optical Engineering, vol. 11786, Optical Methods for Inspection, Characterization, and Imaging of Biomaterials V 2021, Virtual, Online, Germany, 21/06/21 . https://doi.org/10.1117/12.2596966
Accession number :
edsair.doi.dedup.....2276dddf189f928d8c69d0c57ae8820c
Full Text :
https://doi.org/10.1117/12.2596966