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Vision- and Health-Related Quality of Life in Patients With Behcet Uveitis
- Publication Year :
- 2010
- Publisher :
- AMER MEDICAL ASSOC, 2010.
-
Abstract
- Objective: To investigate vision- and health-related quality of life in patients with Behcet disease. Methods: Fifty-one consecutive patients with Behcet uveitis were enrolled in the study from January 1 through June 30, 2008. The National Eye Institute Visual Functioning Questionnaire (NEI-VFQ-25) and the 36-Item Short Form Health Survey (SF-36) were administered. Sociodemographic and clinical data were also collected. Main outcome measures were comparison of the NEI-VFQ-25 and SF-36 subscale item scores among subgroups and multivariate analysis of the NEI-VFQ-25 and SF-36 subscale item scores. Results: Patients rated the general health subscale score of the NEI-VFQ-25 and all subscale item scores of the SF-36 lower than the NEI-VFQ-25 subscales related to vision. The NEI-VFQ-25 subscale item scores showed significant differences with respect to age, educational level, Behcet uveitis activity and severity, and visual acuity in the better and worse eyes. The SF-36 subscale item scores revealed significant differences according to sex, educational level, and the systemic treatment used. In the best model of linear regression, independent variables accounted for 57.0% of the variance in the NEI-VFQ-25 subscale item (color vision subscale; adjusted R 2 =0.57, P < .001) and for only 23.0% of the variance in the SF-36 subscale item score (role limitation owing to emotional problems subscale; adjusted R 2 =0.23, P=.004). Conclusions: General health is more affected than visual functioning in patients with Behcet uveitis. Sociodemographic and clinical variables had a significant effect on vision- and health-related quality of life. Multivariate analysis of the NEI-VFQ-25 and SF-36 subscales revealed that each subscale item score is affected by additional factor(s) other than those analyzed here.
- Subjects :
- Adult
Male
medicine.medical_specialty
Multivariate analysis
Visual acuity
Adolescent
genetic structures
SF-36
Health Status
Eye disease
Visual Acuity
QUESTIONNAIRE
Systemic therapy
THERAPY
DISEASE
Uveitis
Young Adult
TURKISH VERSION
Quality of life
Sickness Impact Profile
Surveys and Questionnaires
Humans
Medicine
In patient
Prospective Studies
VALIDITY
Vision, Ocular
business.industry
INTERFERON ALPHA-2A
Behcet Syndrome
Middle Aged
medicine.disease
Health Surveys
CANCER
eye diseases
Ophthalmology
RELIABILITY
Quality of Life
Behcet uveitis
Physical therapy
Educational Status
Female
medicine.symptom
business
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....22ca17f86a8895e0fa4dc30b04dc8417