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The Collaborative Cross, a community resource for the genetic analysis of complex traits
- Source :
- Nature genetics, Nature Genetics, 36(11), 1133-1137. Nature Publishing Group
- Publication Year :
- 2004
- Publisher :
- Nature Publishing Group, 2004.
-
Abstract
- The goal of the Complex Trait Consortium is to promote the development of resources that can be used to understand, treat and ultimately prevent pervasive human diseases. Existing and proposed mouse resources that are optimized to study the actions of isolated genetic loci on a fixed background are less effective for studying intact potygenic networks and interactions among genes, environments, pathogens and other factors. The Collaborative Cross will provide a common reference panel specifically designed for the integrative analysis of complex systems and will change the way we approach human health and disease.
- Subjects :
- Mice, Inbred Strains
Disease
Breeding
Biology
Community Networks
Genetic analysis
03 medical and health sciences
Human health
0302 clinical medicine
Databases, Genetic
Genetics
Animals
Humans
Systems genetics
Crosses, Genetic
030304 developmental biology
Recombination, Genetic
0303 health sciences
ENVIRONMENT
business.industry
STRAINS
Health services research
Data science
Biotechnology
MICE
Community resource
Trait
Health Resources
Health Services Research
business
030217 neurology & neurosurgery
Subjects
Details
- Language :
- English
- ISSN :
- 15461718 and 10614036
- Volume :
- 36
- Issue :
- 11
- Database :
- OpenAIRE
- Journal :
- Nature Genetics
- Accession number :
- edsair.doi.dedup.....22fbe78c64861214f31a9f84652155be