Supplemental figure 3. gRNAs targeting essential genes are depleted in time from PIM Kinases Are a Potential Prognostic Biomarker and Therapeutic Target in Neuroblastoma

The x-axis depicts the average number of sequencing reads in the untreated/T0 samples. The y-axis depicts the log2 fold change in abundance of gRNAs in the untreated versus T0 population. gRNAs targeting essential genes are depicted in red, gRNAs targeting non-essential genes are depicted in blue, and all other gRNAs in the library are depicted in black