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Hepatitis D virus and liver transplantation: Indications and outcomes
Hepatitis D virus and liver transplantation: Indications and outcomes
- Source :
- World Journal of Hepatology
- Publication Year :
- 2021
- Publisher :
- Baishideng Publishing Group Inc., 2021.
-
Abstract
- Hepatitis D virus (HDV) is a dependent virus that relies on hepatitis B virus for its replication and transmission. Chronic hepatitis D is a severe form of viral hepatitis that can result in end stage liver disease. Currently, pegylated interferon alpha is the only approved therapy for chronic HDV infection and is associated with significant side effects. Liver transplantation (LT) is the only treatment option for patients with end-stage liver disease, hepatocellular carcinoma, or fulminant hepatitis due to coinfection with HDV. As LT for HDV and hepatitis B virus coinfection is uncommon in the United States, most data on the long-term impact of LT on HDV are from international centers. In this review, we discuss the indications and results of LT with treatment options in HDV patients.
- Subjects :
- Hepatocellular carcinoma
viruses
medicine.disease_cause
03 medical and health sciences
Liver disease
Hepatitis delta virus
0302 clinical medicine
Pegylated interferon
medicine
Fulminant hepatitis
Liver transplant
Hepatitis B virus
Hepatology
business.industry
virus diseases
Minireviews
Hepatitis B immunoglobins
biochemical phenomena, metabolism, and nutrition
medicine.disease
Virology
030220 oncology & carcinogenesis
Coinfection
030211 gastroenterology & hepatology
Hepatitis D virus
business
Viral hepatitis
medicine.drug
Subjects
Details
- ISSN :
- 19485182
- Volume :
- 13
- Database :
- OpenAIRE
- Journal :
- World Journal of Hepatology
- Accession number :
- edsair.doi.dedup.....23de07a1e66db2bbd0ee97359cf28b85
- Full Text :
- https://doi.org/10.4254/wjh.v13.i3.291