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Development of elexacaftor - tezacaftor - ivacaftor: Highly effective CFTR modulation for the majority of people with Cystic Fibrosis
- Source :
- Expert review of respiratory medicine. 15(6)
- Publication Year :
- 2020
-
Abstract
- Introduction: Cystic fibrosis (CF), the most common life-shortening inherited disorder in people of European descent, also occurs in other ethnicities. The identification of the disease, the isolat...
- Subjects :
- Pulmonary and Respiratory Medicine
Indoles
Pyrrolidines
Cystic Fibrosis
Pyridines
Cystic Fibrosis Transmembrane Conductance Regulator
Disease
Quinolones
Bioinformatics
Aminophenols
Cystic fibrosis
European descent
Ivacaftor
03 medical and health sciences
0302 clinical medicine
medicine
Immunology and Allergy
Humans
030212 general & internal medicine
Benzodioxoles
Chloride Channel Agonists
business.industry
Public Health, Environmental and Occupational Health
Precision medicine
medicine.disease
Drug Combinations
030228 respiratory system
Mutation
Tezacaftor
Pyrazoles
Identification (biology)
business
medicine.drug
Subjects
Details
- ISSN :
- 17476356
- Volume :
- 15
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Expert review of respiratory medicine
- Accession number :
- edsair.doi.dedup.....23ed70941b43ca8224393e7c5755b023