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The protein folding transition state: Insights from kinetics and thermodynamics
- Source :
- E-Prints Complutense. Archivo Institucional de la UCM, instname, E-Prints Complutense: Archivo Institucional de la UCM, Universidad Complutense de Madrid
- Publication Year :
- 2010
- Publisher :
- American Institute of Physics, 2010.
-
Abstract
- We perform extensive lattice Monte Carlo simulations of protein folding to construct and compare the equilibrium and the kinetic transition state ensembles of a model protein that folds to the native state with two-state kinetics. The kinetic definition of the transition state is based on the folding probability analysis method, and therefore on the selection of conformations with 0.4
- Subjects :
- Phase transition
Protein Folding
Quantitative Biology::Biomolecules
Chemistry
Protein Conformation
Monte Carlo method
General Physics and Astronomy
Thermodynamics
Phi value analysis
Phase Transition
Folding (chemistry)
Kinetics
Protein structure
Química física
Probability distribution
Protein folding
Statistical physics
Downhill folding
Physical and Theoretical Chemistry
Monte Carlo Method
Probability
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- E-Prints Complutense. Archivo Institucional de la UCM, instname, E-Prints Complutense: Archivo Institucional de la UCM, Universidad Complutense de Madrid
- Accession number :
- edsair.doi.dedup.....2411d3e62dfa60686733c546524d52f5