A pilot precision medicine trial for children with diffuse intrinsic pontine glioma-PNOC003: A report from the Pacific Pediatric Neuro-Oncology Consortium

Authors :: David A. Solomon
Lindsay Kilburn
Cassie Kline
Anu Banerjee
Javad Nazarian
Payal Jain
Bo Zhang
Nathalene Truffaux
Joanna J. Phillips
Michael D. Prados
Sara A. Byron
Alison Roos
Kellie J. Nazemi
Sara Nasser
Sabine Mueller
Winnie S. Liang
Yuankun Zhu
Angela J. Waanders
John G. Kuhn
Michael E. Berens
Suresh N. Magge
John R. Crawford
Annette M. Molinaro
Roger J. Packer
Eshini Panditharatna
Adam C. Resnick
Nalin Gupta
Claudia Petritsch
Source :: International journal of cancer, vol 145, iss 7, Mueller, Sabine; Jain, Payal; Liang, Winnie S; Kilburn, Lindsay; Kline, Cassie; Gupta, Nalin; et al.(2019). A pilot precision medicine trial for children with diffuse intrinsic pontine glioma-PNOC003: A report from the Pacific Pediatric Neuro-Oncology Consortium.. International journal of cancer. doi: 10.1002/ijc.32258. UCSF: Retrieved from: http://www.escholarship.org/uc/item/9b60x2n8
Publication Year :: 2019
Publisher :: eScholarship, University of California, 2019.
Abstract: This clinical trial evaluated whether whole exome sequencing (WES) and RNA sequencing (RNAseq) of paired normal and tumor tissues could be incorporated into a personalized treatment plan for newly diagnosed patients (

Subjects :: Oncology
Male
Cancer Research
Pilot Projects
Whole Exome Sequencing
Circulating Tumor DNA
Histones
0302 clinical medicine
Pediatric Neuro-Oncology
Treatment plan
Antineoplastic Combined Chemotherapy Protocols
Brain Stem Neoplasms
Molecular Targeted Therapy
Precision Medicine
Child
Exome sequencing
Cancer
next generation sequencing
Pediatric
genomics-guided clinical trial
Circulating tumor DNA
030220 oncology & carcinogenesis
Child, Preschool
Female
Sequence Analysis
Biotechnology
Adult
medicine.medical_specialty
Adolescent
Pediatric Cancer
precision medicine
Oncology and Carcinogenesis
DNA sequencing
03 medical and health sciences
Young Adult
Rare Diseases
Clinical Research
Internal medicine
Exome Sequencing
medicine
Genetics
Humans
Oncology & Carcinogenesis
Preschool
Whole genome sequencing
Whole Genome Sequencing
business.industry
Sequence Analysis, RNA
Diffuse Intrinsic Pontine Glioma
Human Genome
Neurosciences
Precision medicine
Brain Disorders
Clinical trial
Brain Cancer
Good Health and Well Being
Feasibility Studies
RNA
business

Database :: OpenAIRE
Journal :: International journal of cancer, vol 145, iss 7, Mueller, Sabine; Jain, Payal; Liang, Winnie S; Kilburn, Lindsay; Kline, Cassie; Gupta, Nalin; et al.(2019). A pilot precision medicine trial for children with diffuse intrinsic pontine glioma-PNOC003: A report from the Pacific Pediatric Neuro-Oncology Consortium.. International journal of cancer. doi: 10.1002/ijc.32258. UCSF: Retrieved from: http://www.escholarship.org/uc/item/9b60x2n8
Accession number :: edsair.doi.dedup.....2414e794b14e0994f75da1266c15d7d7
Full Text :: https://doi.org/10.1002/ijc.32258.

Full Text Access

Tools