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The clinical characteristics of two anti-OJ (anti-isoleucyl-tRNA synthetase) autoantibody-positive interstitial lung disease patients with polymyositis/dermatomyositis
- Source :
- Internal medicine (Tokyo, Japan). 51(24)
- Publication Year :
- 2012
-
Abstract
- We herein report the clinical and laboratory characteristics of two anti-OJ (anti-isoleucyl-tRNA synthetase) autoantibody-positive interstitial lung disease patients with polymyositis/dermatomyositis (PM/DM). We compared these characteristics with previously published findings. Previous reports and our present cases show that anti-OJ autoantibody-positive interstitial lung disease (ILD) patients with PM/DM lack the manifestations of Raynaud's phenomenon and sclerodactyly and show good prognoses and responses to glucocorticoid therapy. These results indicate that the presence of anti-OJ autoantibodies may be useful for predicting the prognosis of ILD and its clinical course in PM/DM patients.
- Subjects :
- Isoleucine-tRNA Ligase
Male
Pathology
medicine.medical_specialty
Polymyositis
Dermatomyositis
Internal Medicine
medicine
Humans
Aged
Autoantibodies
business.industry
Isoleucyl-tRNA synthetase
Interstitial lung disease
Clinical course
Autoantibody
Sclerodactyly
General Medicine
medicine.disease
Polymyositis-Dermatomyositis
Female
medicine.symptom
business
Lung Diseases, Interstitial
Subjects
Details
- ISSN :
- 13497235
- Volume :
- 51
- Issue :
- 24
- Database :
- OpenAIRE
- Journal :
- Internal medicine (Tokyo, Japan)
- Accession number :
- edsair.doi.dedup.....24d6d9c20044339353ef54dacf58b08c