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The clinical characteristics of two anti-OJ (anti-isoleucyl-tRNA synthetase) autoantibody-positive interstitial lung disease patients with polymyositis/dermatomyositis

Authors :
Satoshi Ubukata
Takao Fujii
Machiko Arita
Tsuneyo Mimori
Satoshi Konishi
Mika Saigusa
Yasushi Fukuda
Kei Kunimasa
Maki Tanaka
Kazuya Tsubouchi
Takashi Nakazawa
Tadashi Ishida
Hiroaki Nakagawa
Yohei Korogi
Source :
Internal medicine (Tokyo, Japan). 51(24)
Publication Year :
2012

Abstract

We herein report the clinical and laboratory characteristics of two anti-OJ (anti-isoleucyl-tRNA synthetase) autoantibody-positive interstitial lung disease patients with polymyositis/dermatomyositis (PM/DM). We compared these characteristics with previously published findings. Previous reports and our present cases show that anti-OJ autoantibody-positive interstitial lung disease (ILD) patients with PM/DM lack the manifestations of Raynaud's phenomenon and sclerodactyly and show good prognoses and responses to glucocorticoid therapy. These results indicate that the presence of anti-OJ autoantibodies may be useful for predicting the prognosis of ILD and its clinical course in PM/DM patients.

Details

ISSN :
13497235
Volume :
51
Issue :
24
Database :
OpenAIRE
Journal :
Internal medicine (Tokyo, Japan)
Accession number :
edsair.doi.dedup.....24d6d9c20044339353ef54dacf58b08c