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Investigating the integrate and fire model as the limit of a random discharge model: a stochastic analysis perspective

Authors :
Jian-Guo Liu
Ziheng Wang
Zhennan Zhou
Yuan Zhang
Yantong Xie
Source :
Mathematical Neuroscience and Applications. 1
Publication Year :
2021
Publisher :
Centre pour la Communication Scientifique Directe (CCSD), 2021.

Abstract

In the mean field integrate-and-fire model, the dynamics of a typical neuron within a large network is modeled as a diffusion-jump stochastic process whose jump takes place once the voltage reaches a threshold. In this work, the main goal is to establish the convergence relationship between the regularized process and the original one where in the regularized process, the jump mechanism is replaced by a Poisson dynamic, and jump intensity within the classically forbidden domain goes to infinity as the regularization parameter vanishes. On the macroscopic level, the Fokker-Planck equation for the process with random discharges (i.e. Poisson jumps) are defined on the whole space, while the equation for the limit process is on the half space. However, with the iteration scheme, the difficulty due to the domain differences has been greatly mitigated and the convergence for the stochastic process and the firing rates can be established. Moreover, we find a polynomial-order convergence for the distribution by a re-normalization argument in probability theory. Finally, by numerical experiments, we quantitatively explore the rate and the asymptotic behavior of the convergence for both linear and nonlinear models.<br />This is a new version of the existed paper and I should not submit a new one. Please see arXiv:2009.04679

Details

ISSN :
28010159
Volume :
1
Database :
OpenAIRE
Journal :
Mathematical Neuroscience and Applications
Accession number :
edsair.doi.dedup.....2606b9f19628df4db39e4ac6a1b63260