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Safe Pseudovirus-based Assay for Neutralization Antibodies against Influenza A(H7N9) Virus
- Source :
- Emerging Infectious Diseases, Vol 19, Iss 10, Pp 1685-1687 (2013), Emerging Infectious Diseases
- Publication Year :
- 2013
- Publisher :
- Centers for Disease Control and Prevention, 2013.
-
Abstract
- Serologic studies are urgently needed to assist in understanding an outbreak of influenza A(H7N9) virus. However, a biosafety level 3 laboratory is required for conventional serologic assays with live lethal virus. We describe a safe pseudovirus-based neutralization assay with preliminary assessment using subtype H7N9-infected samples and controls.
- Subjects :
- Microbiology (medical)
Epidemiology
Genetic Vectors
serology
lcsh:Medicine
Biology
Influenza A Virus, H7N9 Subtype
Neutralization
Virus
Serology
lcsh:Infectious and parasitic diseases
Biosafety level
Influenza, Human
neutralization tests
Humans
viruses
lcsh:RC109-216
Cloning, Molecular
Aged
Aged, 80 and over
subtype H7N9
pseudovirus
Lentivirus
lcsh:R
Dispatch
Outbreak
Influenza a
Middle Aged
biology.organism_classification
Antibodies, Neutralizing
Virology
Influenza
HEK293 Cells
Infectious Diseases
biology.protein
Capsid Proteins
Antibody
Genetic Engineering
Subjects
Details
- Language :
- English
- ISSN :
- 10806059 and 10806040
- Volume :
- 19
- Issue :
- 10
- Database :
- OpenAIRE
- Journal :
- Emerging Infectious Diseases
- Accession number :
- edsair.doi.dedup.....260c69810575ec73b145d38a9b1a4a23