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Factors determining weight gain in adults and relation with glucose tolerance
- Source :
- Clinical Endocrinology. 78:858-864
- Publication Year :
- 2013
- Publisher :
- Wiley, 2013.
-
Abstract
- SummaryObjective Modifications in lifestyle, diet and certain clinical events are major contributors for the high prevalence of obesity. The aim of this study was to assess factors associated with weight gain in a population of Spanish adults. Design The study was undertaken in two population-based cohorts from the north and the south of Spain (baseline and after 6 years). The Asturias Study, in the north, included 1034 persons aged 30–75 years, of whom 701 were reassessed. The Pizarra Study, in the south, included 1226 persons aged 18–65 years, of whom 783 were re-evaluated. Both studies involved a nutritional questionnaire, a physical examination and an oral glucose tolerance test (OGTT). Results During the follow-up, 32·3% of the participants lost weight, 34·5% gained fewer than 4 kg and 33·2% gained more than 4 kg. Weight gain was greater in persons younger than 50 years and in those with an initial body mass index below 30. Weight gain was associated with a greater incidence of type 2 diabetes mellitus (T2DM) and abnormal glucose tolerance, whereas weight loss in persons with these disorders was associated with a normal OGTT 6 years later. Persons who took less exercise and those who reported a higher daily calorie intake experienced greater weight gain. Conclusion The longitudinal changes in weight affect the development of T2DM and abnormal glucose tolerance. The weight is a dynamic phenomenon affected by several social customs.
- Subjects :
- Adult
Male
medicine.medical_specialty
Endocrinology, Diabetes and Metabolism
Population
Physical examination
Weight Gain
Endocrinology
Weight loss
Internal medicine
medicine
Humans
Longitudinal Studies
Obesity
education
Life Style
Aged
education.field_of_study
medicine.diagnostic_test
business.industry
Incidence (epidemiology)
Type 2 Diabetes Mellitus
Glucose Tolerance Test
Middle Aged
medicine.disease
Diet
Glucose
Diabetes Mellitus, Type 2
Spain
Female
medicine.symptom
Energy Intake
business
Body mass index
Weight gain
Subjects
Details
- ISSN :
- 03000664
- Volume :
- 78
- Database :
- OpenAIRE
- Journal :
- Clinical Endocrinology
- Accession number :
- edsair.doi.dedup.....2617e534025763e617cab3c1348e4e88