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Tools and Strategies for Malaria Control and Elimination: What Do We Need to Achieve a Grand Convergence in Malaria?

Authors :
Gao Qi
Abdoulaye A. Djimde
Timothy N. C. Wells
Nicole L. Achee
Janet Hemingway
Rima Shretta
David Bell
Source :
PLoS Biology, PLoS Biology, Vol 14, Iss 3, p e1002380 (2016)
Publication Year :
2016
Publisher :
Public Library of Science (PLoS), 2016.

Abstract

Progress made in malaria control during the past decade has prompted increasing global dialogue on malaria elimination and eradication. The product development pipeline for malaria has never been stronger, with promising new tools to detect, treat, and prevent malaria, including innovative diagnostics, medicines, vaccines, vector control products, and improved mechanisms for surveillance and response. There are at least 25 projects in the global malaria vaccine pipeline, as well as 47 medicines and 13 vector control products. In addition, there are several next-generation diagnostic tools and reference methods currently in development, with many expected to be introduced in the next decade. The development and adoption of these tools, bolstered by strategies that ensure rapid uptake in target populations, intensified mechanisms for information management, surveillance, and response, and continued financial and political commitment are all essential to achieving global eradication.<br />Malaria elimination in many settings will not be possible without new vaccines, drugs, and vector control products. Although a healthy pipeline of new products in each of these areas has been developed over the past decade, significant work is required to bring these products to market and deploy optimal strategies for their use.

Details

ISSN :
15457885
Volume :
14
Database :
OpenAIRE
Journal :
PLOS Biology
Accession number :
edsair.doi.dedup.....263d29027177aade8db29c5a3a6d7bce
Full Text :
https://doi.org/10.1371/journal.pbio.1002380