Back to Search
Start Over
Gallbladder Gallstone Disease Is Associated with Newly Diagnosed Coronary Artery Atherosclerotic Disease: A Cross-Sectional Study
- Source :
- PLoS ONE, Vol 8, Iss 9, p e75400 (2013), PLoS ONE
- Publication Year :
- 2013
- Publisher :
- Public Library of Science (PLoS), 2013.
-
Abstract
- Background and Aims The association between gallstone disease and coronary artery atherosclerotic disease (CAD) remains unclear. To clarify their relationship, patients with CAD newly diagnosed by coronary angiography were investigated in this cross-sectional study. Methods The study cohort consisted of 1,270 patients undergoing coronary angiography for the first time between January 2007 and September 2011. Patients with ≥50% diameter stenosis in any major coronary artery on coronary angiography were defined as being CAD positive (n = 766) and those with no stenosis as CAD negative (n = 504). Multivariate logistic regression was used to investigate the relationship between gallstone disease and CAD. The odds ratios (OR) of factors associated with CAD were calculated. In addition, CAD-positive and CAD-negative patients were matched one-to-one by age, gender and metabolic syndrome (MetS), and the association between gallbladder disease and CAD was determined. Results The prevalence of gallstone disease was significantly higher in CAD-positive than in CAD negative patients (149/766 [19.5%] vs 57/504 [11.3%], P
- Subjects :
- Male
medicine.medical_specialty
Cross-sectional study
Gallbladder disease
lcsh:Medicine
Coronary Artery Disease
Gallstones
Coronary Angiography
Coronary artery disease
Internal medicine
medicine
Humans
cardiovascular diseases
lcsh:Science
Aged
Multidisciplinary
business.industry
Gallbladder
lcsh:R
Coronary Stenosis
Odds ratio
Middle Aged
medicine.disease
Stenosis
Cross-Sectional Studies
medicine.anatomical_structure
Cardiology
Female
lcsh:Q
Metabolic syndrome
business
Research Article
Subjects
Details
- ISSN :
- 19326203
- Volume :
- 8
- Database :
- OpenAIRE
- Journal :
- PLoS ONE
- Accession number :
- edsair.doi.dedup.....263e4395c1472b254271df27361e72ff