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Two new isopimarane diterpenoids from the endophytic fungus Xylaria sp. SNB-GTC2501
- Source :
- Tetrahedron Letters, Tetrahedron Letters, Elsevier, 2015, 56 (31), pp.4596-4598. ⟨10.1016/j.tetlet.2015.06.022⟩
- Publication Year :
- 2015
- Publisher :
- HAL CCSD, 2015.
-
Abstract
- Two new isopimarane diterpenoids, xylabisboein A (1) and B (2), as well as three known secondary metabolites (i.e., (−)-5-methylmellein (3), mellein-5-carboxylic acid (4) and ergosterol peroxide (5)), were isolated from a solid culture of the endophytic fungus Xylaria sp. SNB-GTC2501. The structures were elucidated by spectroscopic analysis and the absolute configuration of xylabisboein A (1) was determined by X-ray crystallographic analysis. All of the compounds were tested for their antimicrobial and cytotoxic activities.
- Subjects :
- Ergosterol peroxide
010405 organic chemistry
Stereochemistry
Chemistry
Organic Chemistry
Absolute configuration
Endophytic fungus
Xylaria sp
Antimicrobial
01 natural sciences
Biochemistry
3. Good health
0104 chemical sciences
010404 medicinal & biomolecular chemistry
chemistry.chemical_compound
[CHIM.ANAL]Chemical Sciences/Analytical chemistry
Drug Discovery
ComputingMilieux_MISCELLANEOUS
Subjects
Details
- Language :
- English
- ISSN :
- 00404039
- Database :
- OpenAIRE
- Journal :
- Tetrahedron Letters, Tetrahedron Letters, Elsevier, 2015, 56 (31), pp.4596-4598. ⟨10.1016/j.tetlet.2015.06.022⟩
- Accession number :
- edsair.doi.dedup.....2710c83f4d94756c70f740a20ee31c48
- Full Text :
- https://doi.org/10.1016/j.tetlet.2015.06.022⟩