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The relation between blood and tissue magnesium levels and development of atrial fibrillation after coronary artery bypass surgery
- Source :
- Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology. 10(5)
- Publication Year :
- 2010
-
Abstract
- Objective: Atrial fibrillation (AF) is a common complication of cardiovascular surgery and its mechanisms are not well understood. The aim of our study was a prospective investigation of the relationship between AF development and tissue or blood magnesium levels. Methods: This prospective observational study evaluated 20 patients undergoing elective initial coronary artery bypass graft (CABG) surgery. Right atrial appendage and skeletal muscle samples were obtained for tissue magnesium level analysis before, during (at 60th minute) and 30 minutes after cardiopulmonary bypass (CPB) with simultaneous blood samples. Daily measurements of blood Mg levels and continuous monitoring for AF were performed for 7 postoperative days. Statistical analyses were performed using ANOVA, independent samples t and Chi-square tests. Results: AF developed in 5 out of 20 patients during postoperative period (25%). Patients with or without AF did not differ in terms of tissue and blood magnesium levels during and early after CPB and during 7 days after the operation. Blood magnesium levels were significantly higher in the whole study population on postoperative days 3 through 7 (day 3 - 1.13±0.11 mmol/L; day 4-, 1.18±0.07 mmol/L; day 5-1.15±0.10 mmol/L; day 6-1.17±0.08 mmol/L; and day 7, 1.22±0.08 mmol/L) compared to day 1 and day 2 (day 1-0.96±0.13 mmol/L and day 2-1.02±0.12 mmol/L; p=0.002 for all comparisons). Conclusion: Although patients with and without AF did not significantly differ with regard to blood and tissue magnesium levels, the coincidence of an early postoperative reduction in magnesium levels in all patients and occurrence of all AF incidences at this time period suggests a potential association deserving further investigation.
- Subjects :
- Male
medicine.medical_specialty
chemistry.chemical_element
law.invention
Coronary artery bypass surgery
law
Internal medicine
Atrial Fibrillation
medicine
Cardiopulmonary bypass
Humans
Telemetry
Magnesium
Prospective Studies
Coronary Artery Bypass
Prospective cohort study
Muscle, Skeletal
Aged
business.industry
Atrial fibrillation
Length of Stay
Middle Aged
medicine.disease
Intensive Care Units
medicine.anatomical_structure
chemistry
Elective Surgical Procedures
Preoperative Period
Cardiology
Population study
Female
Cardiology and Cardiovascular Medicine
Complication
business
Artery
Subjects
Details
- ISSN :
- 13080032
- Volume :
- 10
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology
- Accession number :
- edsair.doi.dedup.....27140b3140f18cf355ca25aa9e813e49