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Ensuring a Locally Tailored Response to Early Onset Sepsis Screening Meets or Exceeds the Performance of Published Approaches
- Source :
- Hospital Pediatrics. 10:877-883
- Publication Year :
- 2020
- Publisher :
- American Academy of Pediatrics (AAP), 2020.
-
Abstract
- BACKGROUND: Evaluation of well-appearing neonates for early-onset sepsis (EOS) remains controversial. Multiple risk stratification approaches are currently used for the evaluation of EOS. Our aim was to quantify and compare frequency of laboratory evaluation and empirical antibiotics between published and local EOS approaches. METHODS: This retrospective cohort study included 8240 infants born ≥35 + 0/7 weeks’ gestation at an institution from October 1, 2014, to March 1, 2018. Excluded from analysis were 156 patients who exhibited either major congenital anomalies or required antibiotics for surgical issues. A total of 1680 patient charts with risk factors for EOS were reviewed for further demographic data, clinical presentation, laboratory results, and probable recommendations from 4 EOS risk assessment approaches. RESULTS: Laboratory evaluation recommendation was 7.1% for Centers for Disease Control and Prevention 2010 guidelines and local 2016 EOS algorithm, 6% for local 2019 EOS algorithm, and 5.9% for Kaiser Permanente neonatal EOS calculator (neonatal EOS calculator). Antibiotic recommendation was 6% for 2010 Centers for Disease Control and Prevention guidelines, 4.3% for neonatal EOS calculator, and 3.3% for local 2016 and 2019 EOS algorithms. CONCLUSIONS: Of the 4 approaches reviewed, the local 2019 EOS algorithm and the neonatal EOS calculator were similar in recommending the lowest frequency of laboratory evaluation and the local 2016 and 2019 EOS algorithms had the lowest recommended antibiotic usage in this population.
- Subjects :
- medicine.medical_specialty
Population
Demographic data
Risk Assessment
Pediatrics
03 medical and health sciences
0302 clinical medicine
Early onset sepsis
Risk Factors
Sepsis
030225 pediatrics
Humans
Medicine
030212 general & internal medicine
education
Retrospective Studies
education.field_of_study
business.industry
Infant, Newborn
Infant
Retrospective cohort study
General Medicine
Laboratory results
Disease control
Anti-Bacterial Agents
Pediatrics, Perinatology and Child Health
Risk stratification
Emergency medicine
Neonatal Sepsis
business
Risk assessment
Subjects
Details
- ISSN :
- 21541671 and 21541663
- Volume :
- 10
- Database :
- OpenAIRE
- Journal :
- Hospital Pediatrics
- Accession number :
- edsair.doi.dedup.....2793f3ccb865b75cd96d35d9c8c6d5fa