Additional file 2: of Subgroup-specific prognostic signaling and metabolic pathways in pediatric medulloblastoma

Figure S1. Kaplan-Meier subgroup analysis. A, 10-year Kaplan-Meier subgroup analysis in the exploratory dataset. B, 10-year Kaplan-Meier subgroup analysis in the validation dataset. Figure S2. Association between the average relative expression of prognostic core genes and subtype and clinical characteristics. A, Boxplots of relative expression of 31 core genes from the top two PID pathways in SHH subgroup. B, Boxplots of relative expression of 20 core genes from the top two PID pathways in Group 3. C, Boxplots of relative expression of 31 core genes from the top two PID pathways in Group 4. A, large cell/anaplastic (LCA); C, Classic; D, Desmoplastic; M, Medulloblastoma with extensive nodularity (MBEN). *, Mann–Whitney U test p-value 0.4. Figure S6. Differential expressions of the prognostic genes identified in Group 4. A, Boxplots of gene expressions in four subgroups. B, Differential gene expressions with Mann–Whitney U test p-values according to the status of chromosome aberrations in Group 4. (PDF 1629 kb)