Back to Search
Start Over
Dorsal attention network centrality increases during recovery from acute stress exposure
- Source :
- NeuroImage: Clinical, Vol 31, Iss, Pp 102721-(2021), Broeders, T A A, Schoonheim, M M, Vink, M, Douw, L, Geurts, J J G, van Leeuwen, J M C & Vinkers, C H 2021, ' Dorsal attention network centrality increases during recovery from acute stress exposure ', NeuroImage: Clinical, vol. 31, 102721 . https://doi.org/10.1016/j.nicl.2021.102721, NeuroImage: Clinical, 31:102721. Elsevier BV, Neuroimage. Clinical, 31, pp. 1-9, Neuroimage. Clinical, 31, 1-9, NeuroImage : Clinical
- Publication Year :
- 2021
- Publisher :
- Elsevier, 2021.
-
Abstract
- Highlights • Dorsal attention network (DAN) centrality increased during stress recovery in healthy controls. • Healthy siblings of schizophrenia patients show a similar increase during stress recovery. • Bipolar disorder patients show no network changes during stress recovery.<br />Stress is a major risk factor for the development of almost all psychiatric disorders. In addition to the acute stress response, an efficient recovery in the aftermath of stress is important for optimal resilience. Increased stress vulnerability across psychiatric disorders may therefore be related to altered trajectories during the recovery phase following stress. Such recovery trajectories can be quantified by changes in functional brain networks. This study therefore evaluated longitudinal functional network changes related to stress in healthy individuals (N = 80), individuals at risk for psychiatric disorders (healthy siblings of schizophrenia patients) (N = 39), and euthymic bipolar I disorder (BD) patients (N = 36). Network changes were evaluated before and at 20 and 90 min after onset of an experimental acute stress task (Trier Social Stress Test) or a control condition. Whole-brain functional networks were analyzed using eigenvector centrality as a proxy for network importance, centrality change over time was related to the acute stress response and recovery for each group. In healthy individuals, centrality of the dorsal attention network (DAN; p = 0.007) changed over time in relation to stress. More specifically, DAN centrality increased during the recovery phase after acute stress exposure (p = 0.020), while no DAN centrality change was observed during the initial stress response (p = 0.626). Such increasing DAN centrality during stress recovery was also found in healthy siblings (p = 0.016), but not in BD patients (p = 0.554). This study highlights that temporally complex and precise changes in network configuration are vital to understand the response to and recovery from stress.
- Subjects :
- Bipolar I disorder
Bipolar disorder
Cognitive Neuroscience
media_common.quotation_subject
Computer applications to medicine. Medical informatics
Stress-related disorders Donders Center for Medical Neuroscience [Radboudumc 13]
R858-859.7
Dorsal attention network
050105 experimental psychology
03 medical and health sciences
Functional connectivity
0302 clinical medicine
All institutes and research themes of the Radboud University Medical Center
Recovery
Task-positive network
mental disorders
Trier social stress test
Medicine
Humans
Centrality
0501 psychology and cognitive sciences
Radiology, Nuclear Medicine and imaging
Risk factor
Acute stress
RC346-429
media_common
business.industry
Siblings
05 social sciences
Brain
Regular Article
medicine.disease
Magnetic Resonance Imaging
Neurology
Schizophrenia
Neurology (clinical)
Psychological resilience
sense organs
Neurology. Diseases of the nervous system
business
030217 neurology & neurosurgery
Clinical psychology
Subjects
Details
- Language :
- English
- ISSN :
- 22131582
- Volume :
- 31
- Database :
- OpenAIRE
- Journal :
- NeuroImage: Clinical
- Accession number :
- edsair.doi.dedup.....27bc832696b2b22ebb674a4e4cb58b1d