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Early Diagnosis of Occult Blood of Colorectal Cancer Based on Nano-Colloidal Gold Sandwich Immunochromatography

Authors :
Yongying Wu
Zou Yin
Dayong Tian
Xiaolin Yang
Zhihua Zhou
Hui Yang
Jiaoyan Zhang
Yixia Yang
Fangyang Lu
Zhitao Chen
Tao Tang
Source :
Journal of biomedical nanotechnology. 17(8)
Publication Year :
2021

Abstract

The development of science and technology has deepened people’s understanding of cancer, changing the management of malignant tumors in the medical field. Given the common precancerous characteristics of colorectal cancer (CRC), researchers studied early CRC screening. The complexity of traditional diagnostics forced medical staff to speed up CRC innovation early screening methods. Here, we prepared nano-colloidal gold raw materials with different particle sizes (15 and 30 nm) and observed the morphological characteristics and properties of the materials. Simultaneously, the nanocolloidal gold double antibody sandwich kit was designed through the optimum pH value and protein content screening experiment. The results of clinical enteroscopy confirmed the important guiding significance of the equipment in early CRC screening.

Details

ISSN :
15507033
Volume :
17
Issue :
8
Database :
OpenAIRE
Journal :
Journal of biomedical nanotechnology
Accession number :
edsair.doi.dedup.....27c72427947b31d4d6f755f58f9fd4fd