Cerebrospinal fluid oligoclonal IgG bands in multiple sclerosis: what does it mean?

ultiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS). Presence of plaques is the main pathological feature of MS, occurring in myelinated axons within the CNS (brain and spi-nal cord). MS is classified as relapsing-remitting MS (RRMS) characterized by attacks, whose symptoms occur so suddenly with subsequent partial or complete recovery; primary-progressive MS (PPMS) with progressive symptoms accumulated over time; and sec-ondary-progressive MS (SPMS), after the initial form of RRMS. The most common type of MS is the relapsing-remitting (when attacks may sequelae or not)