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Beneficial Effect on Surrogate Markers of Heart Failure with Bisoprolol Up-Titration to Recommended Targets in Korean Patients with Heart Failure and Left Ventricular Systolic Dysfunction
- Source :
- Cardiovascular Therapeutics. 34:172-179
- Publication Year :
- 2016
- Publisher :
- Wiley, 2016.
-
Abstract
- INTRODUCTION The objective of this study was to establish the benefit of bisoprolol up-titration toward recommended dosage targets, versus lower-dose maintenance, in heart failure (HF) patients with systolic dysfunction. METHODS Korean HF patients received bisoprolol 1.25 mg/day, incrementally up-titrated toward 10 mg/day in the absence of contraindications. After 26 weeks' treatment, patients were grouped as low-dose (
- Subjects :
- Male
Time Factors
Blood Pressure
030204 cardiovascular system & hematology
Ventricular Function, Left
Ventricular Dysfunction, Left
0302 clinical medicine
Heart Rate
Natriuretic Peptide, Brain
Natriuretic peptide
Clinical endpoint
Drug Dosage Calculations
Pharmacology (medical)
Prospective Studies
030212 general & internal medicine
Exercise Tolerance
Ejection fraction
General Medicine
Middle Aged
Adrenergic beta-1 Receptor Antagonists
Treatment Outcome
Bisoprolol
Practice Guidelines as Topic
Cardiology
Female
Drug Monitoring
Cardiology and Cardiovascular Medicine
medicine.drug
medicine.medical_specialty
Dose
Systole
medicine.drug_class
Drug Administration Schedule
03 medical and health sciences
Predictive Value of Tests
Internal medicine
Republic of Korea
Heart rate
medicine
Humans
Aged
Heart Failure
Pharmacology
business.industry
Stroke Volume
Recovery of Function
medicine.disease
Peptide Fragments
Blood pressure
Heart failure
business
Biomarkers
Subjects
Details
- ISSN :
- 17555914
- Volume :
- 34
- Database :
- OpenAIRE
- Journal :
- Cardiovascular Therapeutics
- Accession number :
- edsair.doi.dedup.....28693110b2d87ace36fac43fc93cbefc