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A multilayered post-GWAS assessment on genetic susceptibility to pancreatic cancer
- Source :
- GENOME MEDICINE, r-FISABIO. Repositorio Institucional de Producción Científica, instname, López de Maturana, E, Rodríguez, J A, Alonso, L, Lao, O, Molina-Montes, E, Martín-Antoniano, I A, Gómez-Rubio, P, Lawlor, R, Carrato, A, Hidalgo, M, Iglesias, M, Molero, X, Löhr, M, Michalski, C, Perea, J, O’Rorke, M, Barberà, V M, Tardón, A, Farré, A, Muñoz-Bellvís, L, Crnogorac-Jurcevic, T, Domínguez-Muñoz, E, Gress, T, Greenhalf, W, Sharp, L, Arnes, L, Cecchini, L, Balsells, J, Costello, E, Ilzarbe, L, Kleeff, J, Kong, B, Márquez, M, Mora, J, O’Driscoll, D, Scarpa, A, Ye, W, Yu, J, García-Closas, M, Kogevinas, M, Rothman, N, Silverman, D T, Albanes, D, Arslan, A A, Beane-Freeman, L, Bracci, P M, Brennan, P, Bueno-de-Mesquita, B, Buring, J, Canzian, F, PanGenEU Investigators & SBC/EPICURO Investigators 2021, ' A multilayered post-GWAS assessment on genetic susceptibility to pancreatic cancer ', Genome Medicine, vol. 13, no. 1, 15 . https://doi.org/10.1186/s13073-020-00816-4, Genome Medicine, r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau, PanGenEU Investigators & SBC/EPICURO Investigators 2021, ' A multilayered post-GWAS assessment on genetic susceptibility to pancreatic cancer ', genome medicine, vol. 13, no. 1, pp. 15 . https://doi.org/10.1186/s13073-020-00816-4, Genome Medicine, Vol 13, Iss 1, Pp 1-18 (2021), WOS:000616492900001, RUO. Repositorio Institucional de la Universidad de Oviedo, Scientia, Dipòsit Digital de Documents de la UAB, Universitat Autònoma de Barcelona
- Publication Year :
- 2021
- Publisher :
- BioMed Central, 2021.
-
Abstract
- The work was partially supported by Fondo de Investigaciones Sanitarias (FIS), Instituto de Salud Carlos III, Spain (PI061614, PI11/01542, PI0902102, PI12/01635, PI12/00815, PI15/01573, PI18/01347); Red Temática de Investigación Cooperativa en Cáncer, Spain (RD12/0036/0034, RD12/0036/ 0050, RD12/0036/0073); Spanish Ministerio de Ciencia, Innovación y Universidades (BFU2017-85926-P)<br />López de Maturana, E., Rodríguez, J.A., Alonso, L., Lao, O., Molina-Montes, E., Martín-Antoniano, I.A., Gómez-Rubio, P., Lawlor, R., Carrato, A., Hidalgo, M., Iglesias, M., Molero, X., Löhr, M., Michalski, C., Perea, J., O’Rorke, M., Barberà, V.M., Tardón, A., Farré, A., Muñoz-Bellvís, L., Crnogorac-Jurcevic, T., Domínguez-Muñoz, E., Gress, T., Greenhalf, W., Sharp, L., Arnes, L., Cecchini, L., Balsells, J., Costello, E., Ilzarbe, L., Kleeff, J., Kong, B., Márquez, M., Mora, J., O’Driscoll, D., Scarpa, A., Ye, W., Yu, J., García-Closas, M., Kogevinas, M., Rothman, N., Silverman, D.T., Albanes, D., Arslan, A.A., Beane-Freeman, L., Bracci, P.M., Brennan, P., Bueno-de-Mesquita, B., Buring, J., Canzian, F., Du, M., Gallinger, S., Gaziano, J.M., Goodman, P.J., Gunter, M., LeMarchand, L., Li, D., Neale, R.E., Peters, U., Petersen, G.M., Risch, H.A., Sánchez, M.J., Shu, X.-O., Thornquist, M.D., Visvanathan, K., Zheng, W., Chanock, S.J., Easton, D., Wolpin, B.M., Stolzenberg-Solomon, R.Z., Klein, A.P., Amundadottir, L.T., Marti-Renom, M.A., Real, F.X., Malats, N., PanGenEU Investigators, SBC/EPICURO Investigators
- Subjects :
- Genetic Phenomena::Genotype::Genetic Predisposition to Disease [PHENOMENA AND PROCESSES]
Complex disease
lcsh:Medicine
Genome-wide association study
Genome
Linkage Disequilibrium
European descent
0302 clinical medicine
Gene Regulatory Networks
neoplasias::neoplasias por localización::neoplasias del sistema digestivo::neoplasias pancreáticas [ENFERMEDADES]
Genetics (clinical)
0303 health sciences
Phenotype
3. Good health
ddc
030220 oncology & carcinogenesis
Molecular Medicine
Malalties congènites
Signal Transduction
Prioritization
Pancreatic cancer risk
Investigative Techniques::Epidemiologic Methods::Epidemiologic Research Design::Genome-Wide Association Study [ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT]
lcsh:QH426-470
Systems biology
In silico
Computational biology
Biology
03 medical and health sciences
SDG 3 - Good Health and Well-being
Cell Line, Tumor
Pancreatic cancer
Genetics
Biomarkers, Tumor
Genetic predisposition
medicine
Genetic susceptibility
Humans
Computer Simulation
Genetic Predisposition to Disease
Genome-wide association analysis
Molecular Biology
Gene
Spatial analysis
fenómenos genéticos::genotipo::predisposición genética a la enfermedad [FENÓMENOS Y PROCESOS]
030304 developmental biology
Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Pancreatic Neoplasms [DISEASES]
Pàncrees - Càncer
Local indices of genome spatial autocorrelation
Genome, Human
3D genomic structure
Research
lcsh:R
Reproducibility of Results
medicine.disease
Human genetics
Pancreatic Neoplasms
lcsh:Genetics
técnicas de investigación::métodos epidemiológicos::diseño de la investigación epidemiológica::estudio de asociación genómica completa [TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS]
Genome-Wide Association Study
Subjects
Details
- ISSN :
- 1756994X
- Database :
- OpenAIRE
- Journal :
- GENOME MEDICINE, r-FISABIO. Repositorio Institucional de Producción Científica, instname, López de Maturana, E, Rodríguez, J A, Alonso, L, Lao, O, Molina-Montes, E, Martín-Antoniano, I A, Gómez-Rubio, P, Lawlor, R, Carrato, A, Hidalgo, M, Iglesias, M, Molero, X, Löhr, M, Michalski, C, Perea, J, O’Rorke, M, Barberà, V M, Tardón, A, Farré, A, Muñoz-Bellvís, L, Crnogorac-Jurcevic, T, Domínguez-Muñoz, E, Gress, T, Greenhalf, W, Sharp, L, Arnes, L, Cecchini, L, Balsells, J, Costello, E, Ilzarbe, L, Kleeff, J, Kong, B, Márquez, M, Mora, J, O’Driscoll, D, Scarpa, A, Ye, W, Yu, J, García-Closas, M, Kogevinas, M, Rothman, N, Silverman, D T, Albanes, D, Arslan, A A, Beane-Freeman, L, Bracci, P M, Brennan, P, Bueno-de-Mesquita, B, Buring, J, Canzian, F, PanGenEU Investigators & SBC/EPICURO Investigators 2021, ' A multilayered post-GWAS assessment on genetic susceptibility to pancreatic cancer ', Genome Medicine, vol. 13, no. 1, 15 . https://doi.org/10.1186/s13073-020-00816-4, Genome Medicine, r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau, PanGenEU Investigators & SBC/EPICURO Investigators 2021, ' A multilayered post-GWAS assessment on genetic susceptibility to pancreatic cancer ', genome medicine, vol. 13, no. 1, pp. 15 . https://doi.org/10.1186/s13073-020-00816-4, Genome Medicine, Vol 13, Iss 1, Pp 1-18 (2021), WOS:000616492900001, RUO. Repositorio Institucional de la Universidad de Oviedo, Scientia, Dipòsit Digital de Documents de la UAB, Universitat Autònoma de Barcelona
- Accession number :
- edsair.doi.dedup.....28ceb522de3e324df2b13636812ee6a1