Back to Search
Start Over
Analyses of paralytic shellfish toxins and biomarkers in a southern Brazilian reservoir
- Source :
- Toxicon : official journal of the International Society on Toxinology. 55(2-3)
- Publication Year :
- 2009
-
Abstract
- The Alagados Reservoir (Brazil) is an important source for the supply of water, recreation and fishery. Since 2002, the occurrence of cyanobacterial blooms (paralytic shellfish toxins - PST producers) have been noted. This study was aimed at the monitoring of PST occurrence in the Reservoir's water and fish. Biomarkers such as ethoxyresorufin-O-deethylase (EROD), glutathione S-transferase (GST), catalase (CAT), and acetylcholinesterase (AchE) activities, lipoperoxidation (LPO), histopathology, and comet assay were analyzed in fish. Water and fish were sampled in spring, summer and autumn. The PST concentrations in water were 5.15, 43.84, and 50.78 ng equiv Saxitoxin/L in the spring, summer and autumn, respectively. The PST muscle concentration was below the limit for shellfish. Gonyautoxins (GTX) were found in water samples and fish muscle, and GTX 5 was the major analogous found in muscle. In the summer samples, the LPO, genetic damage, and the GST and AchE activities increased while in the autumn an increase in EROD activity and genetic damage were observed. In all samplings, histopathological alterations in the fish gills and liver were found. The results showed a seasonal variation in the fishes health, which could be related also to farming activities and to the contaminants bioavailability during the year.
- Subjects :
- Gill
Gills
Veterinary medicine
Toxicology
chemistry.chemical_compound
Water Supply
medicine
Cytochrome P-450 CYP1A1
Animals
Paralytic shellfish poisoning
Muscle, Skeletal
Shellfish
Glutathione Transferase
Saxitoxin
biology
Mutagenicity Tests
food and beverages
Aquatic animal
Eutrophication
medicine.disease
Catalase
Shellfish poisoning
Perciformes
chemistry
Liver
biology.protein
Marine Toxins
Comet Assay
Lipid Peroxidation
Biomarkers
Brazil
Subjects
Details
- ISSN :
- 18793150
- Volume :
- 55
- Issue :
- 2-3
- Database :
- OpenAIRE
- Journal :
- Toxicon : official journal of the International Society on Toxinology
- Accession number :
- edsair.doi.dedup.....28e0d6d6712bc4e80e7b848205b5b83d