Additional file 1 of Contribution of sarcomere gene mutations to left atrial function in patients with hypertrophic cardiomyopathy

Additional file 1: Method S1. DNA preparation. Method S2. Library construction and sequencing of the HCM gene panel. Method S3. Library construction and mtDNA sequencing. Method S4. Data analysis of the mitochondrial genome. Method S5. CMR. Table S1. Summary of 82 genes associated with hypertrophic cardiomyopathy. Supplementary Table S2. Likely pathogenic or Pathogenic variants in the 33 sarcomere associated genes classified according to the refined American College of Medical Genetics and Genomics (ACMG) standards and guidelines for inherited cardiac conditions. Supplementary Table S3. Likely pathogenic or pathogenic variants in the 6 non-sarcomere genes and the 44 mitochondria-related nuclear genes. Supplementary Table S4. Non-haplogroup-associated variants with a GenBank frequency