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Optimization of the automated, CS-2000i™ method for measuring low levels of von Willebrand factor ristocetin cofactor activity (VWF:RCo)

Authors :
Midori Shima
Tomoko Matsumoto
Masahiro Okuda
Keiji Nogami
Source :
International Journal of Hematology. 101:126-132
Publication Year :
2014
Publisher :
Springer Science and Business Media LLC, 2014.

Abstract

Measurements of von Willebrand factor ristocetin cofactor activity (VWF:RCo) are necessary for the diagnosis of von Willebrand disease (VWD). However, the conventional manual glass-plate method is technically demanding, and exhibits high intra-/inter-laboratory variation. An automated technique has been recently described utilizing the CS-2000i™ with specific VWF:RCo reagents, but measurements at lower levels (

Details

ISSN :
18653774 and 09255710
Volume :
101
Database :
OpenAIRE
Journal :
International Journal of Hematology
Accession number :
edsair.doi.dedup.....2a02782f843f81de7e0b98f195275bee
Full Text :
https://doi.org/10.1007/s12185-014-1720-x