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Wide dynamic dose range of VIPAR polymer gel dosimetry
- Source :
- Physics in Medicine and Biology. 46:2143-2159
- Publication Year :
- 2001
- Publisher :
- IOP Publishing, 2001.
-
Abstract
- In this work the extent of the linear dose response and the dynamic dose range of N-vinylpyrrolidone-argon based (VIPAR) polymer gels were investigated. VIPAR gels were irradiated using a 6 MV linear accelerator up to 60 Gy and a Nucletron microSelectron 192Ir HDR brachytherapy source to much higher doses to cover a dose range of two orders of magnitude. They were then MR scanned at 1.5 T to obtain T2-maps. VIPAR gel measurements obtained from the two irradiation regimes were calibrated against ion chamber measurements and dose calculations derived using the AAPM TG-43 protocol respectively. A satisfying agreement between the calibration results derived using the 6 MV x-rays and the 192Ir source was found for doses up to 60 Gy, implying that the response of the VIPAR gels is independent of photon energy and dose rate. A linear R2 dose response up to approximately 40 Gy and a dynamic dose range up to at least approximately 250 Gy were observed. VIPAR gel dose measurements derived using the monoexponentially fitted brachytherapy calibration data were found to be quite accurate.
- Subjects :
- Materials science
medicine.medical_treatment
Brachytherapy
Dose profile
Gel dosimetry
Linear particle accelerator
Calibration
medicine
Humans
Dosimetry
Radiology, Nuclear Medicine and imaging
Irradiation
Argon
Radiological and Ultrasound Technology
business.industry
Dose-Response Relationship, Radiation
Iridium Radioisotopes
Magnetic Resonance Imaging
Ionization chamber
Polyvinyls
Particle Accelerators
Nuclear medicine
business
Algorithms
Biomedical engineering
Subjects
Details
- ISSN :
- 13616560 and 00319155
- Volume :
- 46
- Database :
- OpenAIRE
- Journal :
- Physics in Medicine and Biology
- Accession number :
- edsair.doi.dedup.....2adca0609cba2a069d3db4470400ed83