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Prior outpatient antibacterial therapy as prognostic factor for mortality in hospitalized pneumonia patients
- Source :
- Respiratory Medicine. 100(8):1342-1348
- Publication Year :
- 2006
- Publisher :
- Elsevier BV, 2006.
-
Abstract
- SummaryStudy objectivesTo assess whether prior outpatient treatment is associated with outcome in patients hospitalized for community-acquired pneumonia (CAP).Patients and methodsAll patients with a first hospital admission for CAP between 1995 and 2000 were selected. Patients were divided into two groups, one of patients with use of antibacterial agents prior to hospitalization and one of patients treated as inpatient directly. The main outcome measures were duration of hospital stay and in-hospital mortality.ResultsThe two patient groups comprised 296 and 794 patients, respectively. The median duration of hospital stay was 10 days and was similar for both groups. In patients with respiratory diseases or heart failure, the median duration of hospital stay was 12 and 14 days, respectively. The overall in-hospital mortality was 7.2% and did not largely differ between both groups. In patients with congestive heart failure, the mortality was 9.8% for controls and 23.3% for patients hospitalized after initial outpatient treatment (adjusted OR 2.78, 95% CI 1.01–7.81).ConclusionsPrior outpatient antibacterial therapy is not associated with outcome in hospitalized pneumonia patients. In patients with underlying chronic heart failure, prior outpatient antibiotic is associated with a significant increased mortality.
- Subjects :
- Adult
Male
Pulmonary and Respiratory Medicine
medicine.medical_specialty
Heart disease
Respiratory Tract Diseases
Heart failure
Statistics, Nonparametric
Community-acquired pneumonia
Internal medicine
Epidemiology
Ambulatory Care
medicine
Humans
Hospital Mortality
Treatment Failure
Mortality
Aged
Netherlands
Antibacterial agent
Aged, 80 and over
business.industry
Odds ratio
Pneumonia
Length of Stay
Middle Aged
medicine.disease
Anti-Bacterial Agents
Surgery
Community-Acquired Infections
Antibacterial agents
Ambulatory
Female
business
Subjects
Details
- ISSN :
- 09546111
- Volume :
- 100
- Issue :
- 8
- Database :
- OpenAIRE
- Journal :
- Respiratory Medicine
- Accession number :
- edsair.doi.dedup.....2aedfc18843c02e14e53660d9def33d4
- Full Text :
- https://doi.org/10.1016/j.rmed.2005.11.024