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Unusually strong lipophilicity of 'fat' or 'super' amino-acids, including a new reference value for glycine
- Source :
- Experientia. 36(10)
- Publication Year :
- 1980
-
Abstract
- Lipophilic, steric, electronic, and enzyme resistance characteristics of carboranylalanine, adamantylalanine, neopentylglycine and tert-butylglycine are described. The first 2 amino-acids display lipophilicities 2 orders of magnitude higher than tryptophan.
- Subjects :
- Pharmacology
chemistry.chemical_classification
Steric effects
Stereochemistry
Tryptophan
Glycine
Molecular Conformation
Water
Cell Biology
Orders of magnitude (mass)
Amino acid
Enzymes
Cellular and Molecular Neuroscience
Structure-Activity Relationship
Enzyme
chemistry
Lipophilicity
Molecular Medicine
Neopentylglycine
Amino Acids
Molecular Biology
Protein Binding
Subjects
Details
- ISSN :
- 00144754
- Volume :
- 36
- Issue :
- 10
- Database :
- OpenAIRE
- Journal :
- Experientia
- Accession number :
- edsair.doi.dedup.....2b2578d55147df6a98f4e8ef11a66832