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Pervasive mutations of JAK-STAT pathway genes in classical Hodgkin lymphoma
- Source :
- Blood. 131(22)
- Publication Year :
- 2017
-
Abstract
- Dissecting the pathogenesis of classical Hodgkin lymphoma (cHL), a common cancer in young adults, remains challenging because of the rarity of tumor cells in involved tissues (usually
- Subjects :
- 0301 basic medicine
medicine.medical_specialty
Immunology
DNA Mutational Analysis
Biology
medicine.disease_cause
Biochemistry
Cell Line
03 medical and health sciences
0302 clinical medicine
Internal medicine
Cell Line, Tumor
medicine
Humans
Gene
Janus Kinases
Mutation
Neoplastic
Hematology
Tumor
Lymphoid Neoplasia
JAK-STAT signaling pathway
Cancer
Cell Biology
medicine.disease
GNA13
Cell Line, Tumor, DNA Mutational Analysis, Gene Expression Regulation, Neoplastic, Hodgkin Disease, Humans, Janus Kinases, Mutation, Signal Transduction, STAT Transcription Factors
Hodgkin Disease
Lymphoma
Gene Expression Regulation, Neoplastic
STAT Transcription Factors
030104 developmental biology
Gene Expression Regulation
030220 oncology & carcinogenesis
Cancer research
PTPN1
Signal Transduction
Subjects
Details
- ISSN :
- 15280020
- Volume :
- 131
- Issue :
- 22
- Database :
- OpenAIRE
- Journal :
- Blood
- Accession number :
- edsair.doi.dedup.....2bad8ed99c120a8df0e02b1a311cad95