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Successful treatment of thymoma-associated erythroid hypoplasia and thrombocytopenia with paclitaxel
- Publication Year :
- 2005
- Publisher :
- Elsevier, 2005.
-
Abstract
- respectively. The reticulocyte count reached 3%. Computed tomography of the chest showed a minimal response to chemotherapy. Two additional cycles of paclitaxel were given. The patient’s haematological values and disease have remained stable for 6 months. The best therapy for thymomaassociated cytopenia has not yet been established. We think that antitumour therapies may be effective as in other paraneoplastic syndromes. To our knowledge, this is the first report showing that paclitaxel may be beneficial in the treatment of thymoma-associated haematologic dyscrasias. The role of paclitaxel in the treatment of thymoma is unknown. On the basis of this case, we suggest that paclitaxel at 175 mg/m 2 every 3 weeks may be a promising chemotherapy for advanced or recurrent thymoma.
- Subjects :
- Male
Letter
medicine.medical_treatment
Disease
Cancer staging
Gastroenterology
Dyscrasia
Dexamethasone
chemistry.chemical_compound
Reticulocyte count
hemic and lymphatic diseases
Treatment outcome
Priority journal
Pure red cell anemia
Anemia, aplastic
Diphenhydramine
Paclitaxel
Oncology
Vincristine
Human
Adult
medicine.medical_specialty
Thymoma
Erythroid hypoplasia
Thymus neoplasms
Antineoplastic agents, phytogenic
Ranitidine
Disease association
Internal medicine
Case report
medicine
Humans
Radiology, Nuclear Medicine and imaging
Cyclophosphamide
Blood cell count
Chemotherapy
Cytopenia
business.industry
Hemoglobin determination
Drug administration schedule
Thymic Epithelial Tumor
Thymus Neoplasms
medicine.disease
Monotherapy
Thrombocytopenia
Thrombocyte transfusion
Surgery
chemistry
Clinical feature
Doxorubicin
Erythrocyte transfusion
Prednisone
Cisplatin
business
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....2bb69ce2cfd962c69eef3d77b309219e