Supplemental figure 10 & 11 from Preclinical Characterization of BET Family Bromodomain Inhibitor ABBV-075 Suggests Combination Therapeutic Strategies

Authors :: Yu Shen
Warren M. Kati
Keith F. McDaniel
Saul H. Rosenberg
Steven W. Elmore
Guowei Fang
Fred Kohlhapp
Xin Lu
Tamar Uziel
Lisa Hasvold
Dachun Liu
John K. Pratt
Steve Fidanze
Le Wang
George S. Sheppard
Cherrie K. Donawho
Denise Wilcox
Xiaoli Huang
Scott E. Warder
Emily J. Faivre
Lloyd T. Lam
Leiming Li
Daniel H. Albert
Xiaoyu Lin
Mai H. Bui
Publication Year :: 2023
Publisher :: American Association for Cancer Research (AACR), 2023.
Abstract: ABBV-075 inhibits Bcl-XL transcription and displace BRD4 from Bcl-XL regulatory regions

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