Diastereoselective synthesis of new zwitterionic bicyclic lactams, scaffolds for construction of 2-substituted-4-hydroxy piperidine and its pipecolic acid derivatives

Authors :: Enrique Reyes-Bravo
Dino Gnecco
Jorge R. Juárez
María L. Orea
Sylvain Bernès
David M. Aparicio
Joel L. Terán
Source :: RSC Advances. 12:4187-4190
Publication Year :: 2022
Publisher :: Royal Society of Chemistry (RSC), 2022.
Abstract: The synthesis of new chiral highly functionalized zwitterionic bicyclic lactams starting from acyclic β-enaminoesters derived from (R)-(−)-2-phenylglycinol is described.

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