Early Bactericidal Activity of Delpazolid (LCB01-0371) in Patients with Pulmonary Tuberculosis

Authors :: Ju Sang Kim
Yong-hyun Kim
Sang Haak Lee
Yee Hyung Kim
Jin-woo Kim
Ji Young Kang
Sung Kyoung Kim
Seung Joon Kim
Yun-Seong Kang
Tae-hyung Kim
Jeongha Mok
Min Kwang Byun
Hye Jung Park
Joon-sung Joh
Yong Bum Park
Hyeong-Seok Lim
Hongjo Choi
Seung Heon Lee
Hyejin Kim
Jeongseong Yang
Hyunji Kim
Xianlin Shen
Abdullah Alsultan
InSook Cho
Lawrence Geiter
Tae Sun Shim
Source :: Antimicrobial Agents and Chemotherapy. 66
Publication Year :: 2022
Publisher :: American Society for Microbiology, 2022.
Abstract: Delpazolid, an oxazolidinone, has been studied in non-clinical studies of efficacy and toxicity and Phase 1 clinical studies. Delpazolid has in vitro activity against Gram-positive bacteria, including Mycobacterium tuberculosis .

Subjects :: Adult
Pharmacology
Antitubercular Agents
Sputum
Mycobacterium tuberculosis
Middle Aged
Pyrazinamide
Young Adult
Infectious Diseases
Isoniazid
Humans
Drug Therapy, Combination
Pharmacology (medical)
Tuberculosis, Pulmonary
Oxazolidinones
Aged

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