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Spatial specificity of auxin responses coordinates wood formation
- Source :
- Nature Communications 9 (2018) 1, Nature Communications, 9(1), Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018), Nature Communications
- Publication Year :
- 2018
-
Abstract
- Spatial organization of signalling events of the phytohormone auxin is fundamental for maintaining a dynamic transition from plant stem cells to differentiated descendants. The cambium, the stem cell niche mediating wood formation, fundamentally depends on auxin signalling but its exact role and spatial organization is obscure. Here we show that, while auxin signalling levels increase in differentiating cambium descendants, a moderate level of signalling in cambial stem cells is essential for cambium activity. We identify the auxin-dependent transcription factor ARF5/MONOPTEROS to cell-autonomously restrict the number of stem cells by directly attenuating the activity of the stem cell-promoting WOX4 gene. In contrast, ARF3 and ARF4 function as cambium activators in a redundant fashion from outside of WOX4-expressing cells. Our results reveal an influence of auxin signalling on distinct cambium features by specific signalling components and allow the conceptual integration of plant stem cell systems with distinct anatomies.<br />Auxin activity controls plant stem cell function. Here the authors show that in the cambium, moderate auxin activity restricts cambial stem cell number via ARF5-dependent repression of the stem‐cell‐promoting factor WOX4, while ARF3 and ARF4 promote cambial activity outside of the WOX4‐expression domain.
- Subjects :
- 0301 basic medicine
Plant stem cell
Science
Arabidopsis
General Physics and Astronomy
Biochemie
Biology
Biochemistry
Article
General Biochemistry, Genetics and Molecular Biology
03 medical and health sciences
Plant Growth Regulators
Gene Expression Regulation, Plant
Auxin
Life Science
Cambium
lcsh:Science
Transcription factor
Cell Proliferation
Homeodomain Proteins
chemistry.chemical_classification
Multidisciplinary
Indoleacetic Acids
Arabidopsis Proteins
Gene Expression Profiling
Stem Cells
fungi
Nuclear Proteins
food and beverages
General Chemistry
Plants, Genetically Modified
biology.organism_classification
Wood
Cell biology
DNA-Binding Proteins
030104 developmental biology
Signalling
chemistry
lcsh:Q
Stem cell
EPS
Function (biology)
Signal Transduction
Transcription Factors
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Database :
- OpenAIRE
- Journal :
- Nature Communications 9 (2018) 1, Nature Communications, 9(1), Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018), Nature Communications
- Accession number :
- edsair.doi.dedup.....2c55a36a51d93a1f0cc2aace30005dcd